How Premature Ejaculation Pills Work

How Premature Ejaculation Pills Work?

Premature ejaculation is embarrassing. And it isn’t easy to get rid of it especially if you want to get over it quickly. One of the best ways to treat premature ejaculation is by pills. Over-the-counter premature ejaculation pills provide a quick and risk-free treatment method. How premature ejaculation pills work and how effective these are in curing premature ejaculation?

Let’s find out.

What is a Premature Ejaculation Pill?

Medications that are swallowed once or twice a day for the treatment of premature ejaculation are called premature ejaculation pills. Ejaculation pills use different ingredients and their pros and cons vary depending on the type of ingredients used.

Unlike other ways to delay ejaculation, such as using delay sprays or delay wipes, pills don’t numb your penis. This is what makes pills suitable for long-term treatment. You might not see the effect of pills instantly as opposed to a delay spray that numbs your penis and prepares you for hardcore sex in as low as 10 minutes.

Different ingredients are used in these pills ranging from herbal to synthetic. ProSolution Plus is a leading premature OTC pill that uses herbal ingredients such as roots of plants, fruits, seeds, plant extracts, etc.:

prosolution plus ingredients

Similarly, all the pills you’ll find in the market for delaying ejaculation have different ups and downs based on their ingredients.

How Premature Ejaculation Pills Work?

So how do premature ejaculation pills work?

It depends on the active ingredients in the pill.

How Premature Ejaculation Pills Work

Most pills have antidepressants like escitalopram that jumpstart your mood so you feel better. You may notice that you sleep better and get on with people more easily because you’re less anxious. It also has a mind-blowing effect on the erectile system in men.

Other premature ejaculation pills use selective serotonin reuptake inhibitors (SSRIs) as an antidepressant. Some pills use ingredients that improve blood to your penis that enhances erection and ejaculation.

There is no exact formula medicine to cure premature ejaculation. Manufacturers use different indirect routes to help you delay ejaculation. And this is the reason why premature ejaculation pills use different ingredients and target different parts of your body in different ways.

There are two main types of pills that can help you last longer in bed:

  1. Prescription pills for premature ejaculation
  2. Over-the-counter (OTC) pills.

1. Prescription Pills

These are the pills prescribed by a physician or doctor or expert. You can’t buy prescription pills without a proper prescription by a relevant physician or an expert. For example, dapoxetine is a prescription pill that you can’t buy without a doctor’s prescription:

dapoxetine pill

The two most popular prescription pills for premature ejaculation are:


Dapoxetine (sold as Priligy) is a selective serotonin reuptake inhibitor that significantly increases your ejaculation time. It acts fast and is recommended a tablet 1-3 hours before sex. Yes, you have to have planned sex if you are using dapoxetine.

You can’t take it daily or regularly.

📖 Suggested Reading: Dapoxetine Vs Paroxetine for PE


Lexapro is the brand name of escitalopram which is an antidepressant drug used to treat depression. It is often prescribed as a pill to cure premature ejaculation. It improves your mood and energy and reduces nervousness.

It helps you delay ejaculation indirectly by reducing stress and depression.

2. Over the Counter Pills

Over-the-counter (OTC) pills can be easily purchased online or in local pharmacies without any prescription. These pills mostly consist of supplements that either directly or indirectly delay ejaculation time in men. ProSolution Plus is a common example of an OTC pill for premature ejaculation.

📖 Suggested Reading: Find out everything about ProSolution Plus and how it can help you significantly delay ejaculation in this detailed review.

Most men prefer using OTC pills for premature ejaculation for the following reasons:

  1. No prescription needed. This saves you from the embarrassment of visiting a doctor and sharing a problem that you are reluctant to
  2. No side effects. Most (if not all) OTC pills for premature ejaculation are supplements that are made from natural ingredients. And they don’t have any side effects. It’s like using any supplement to fulfill your body’s nutritional needs via a supplement
  3. Easy to buy. You can buy premature ejaculation OTC medicines online without having to visit a local pharmacy or store
  4. No embarrassment. You can have OTC premature ejaculation supplements delivered to your doorstep in discrete packing. This saves you from the embarrassment of visiting a local store and buying a premature ejaculation medicine
  5. Costeffective. Premature ejaculation OTC drugs are way too inexpensive than prescription pills. For example, 30 tablets of Priligy 30 mg cost $66 while 60 tablets of ProSolution Plus cost you $69.95. 

These benefits make over-the-counter premature ejaculation drugs the best choice for men.

Do Premature Ejaculation Drugs Work?

Some doctors agree that certain drugs have the potential to increase ejaculation time.

Whether the pill you are using will work or not depends on several factors such as:

  • The pill you are using (prescription vs. OTC)
  • Ingredients of the drug
  • The cause and type of premature ejaculation
  • Your medical history.

And so on…

There are tons of variables that it is almost impossible to predict if a certain ejaculation delaying medicine will work or not.

In general, however, these pills work as it has been clinically tested over and over again in several studies as discussed here.

Side Effects of Premature Ejaculation Medicines

Like all other medicines, premature ejaculation drugs also have side effects. The actual side effects (major or minor) depend on the ingredients used. All the leading manufacturers clearly mention side effects on the label so the first thing you need to do is read the label carefully.

Here is a list of the most common side effects that you may experience after using most of the premature ejaculation drugs:

  1. Drowsiness and dizziness
  2. Weakness
  3. Anxiety
  4. Lack of sleep (insomnia)
  5. Dry mouth
  6. Loss of appetite
  7. Constipation.

It is highly recommended to read the description and label before buying a pill.

Alternatives to Premature Ejaculation Medicines

Pills and drugs aren’t the only way to delay ejaculation. If you are skeptical and don’t want to use pills, you can try other options.

Here is a list of the best alternatives to premature ejaculation pills:

1. Delay Sprays

vigrx delay spray bottle

Delay sprays are numbing sprays that numb your penis. Once your penis is numb, it loses its sensitivity leading to an increase in ejaculation time. The numbing sprays use lidocaine or benzocaine to desensitize your penis.

Unlike premature ejaculation pills, delay sprays provide you with a temporary yet instant solution to premature ejaculation. You can last significantly longer in bed with a single spray.

Delay sprays aren’t a cure to PE. This means even if you use delay sprays continuously for years, it won’t cure premature ejaculation. They’re used as a sexual aid to help you last longer in bed.

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2. Delay Wipes

vigrx delay wipes for men

Delay wipes act in the same way as delay sprays but they’re in the form of wipes that are composed of benzocaine (or local anesthetics). These wipes are easily available and highly appreciated by the male community as they’re easy to use, act instantly, and provide you with an intense sexual experience.

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3. Benzocaine Condoms

Benzocaine condoms are used to delay ejaculation. It numbs your penis head temporarily to desensitize it. Benzocaine is attached to the inner side of the condom in solid form. It melts with the heat of your penis and converts it into liquid and gets activated. Your penis won’t get numb instantly rather it needs 5-10 minutes after benzocaine melts.

📢 More from Our Blog: 7 reasons for using condoms to delay ejaculation, 3 best condoms to delay ejaculation, and what is benzocaine.

4. Delay Oils

vigrx oil tube

Premature ejaculation delay oils are highly concentrated plant extracts that help you in delaying ejaculation and climax time significantly. The plant extracts are used in diluted form after the distillation process.

VigRX delay oil is a special product as it contains 7 naturally occurring plant ingredients including ginkgo biloba leaf, Muira Pauma bark extract, hawthorn berry, Epimedium leaf, cuscuta seed extract, asuan red ginseng, and catuaba bark extract.

📖 Suggested Reading: In-depth VigRX oil review.

Final Words

Premature ejaculation pills are an effective way to improve ejaculation time and enjoy powerful sex. If you are using the right medicine, you can control (and even get rid of) premature ejaculation. The way these pills work depends on their ingredients.

If you are using a prescription pill for premature ejaculation, it is most likely an antidepressant that helps you get rid of stress and increases well being. When you feel better, you can do better in bed.

OTC premature ejaculation drugs, on the other hand, use natural and herbal ingredients (mostly plant extracts) to provide your body with necessary nutrients (especially ones that boost sexual performance, stamina, and timing).

Finding and using the right premature ejaculation drug consistently is the key to happy sex life.

Updated: December 26, 2022